Normal Immune System Development in Mice Lacking the Deltex-1 RING Finger Domain
نویسندگان
چکیده
منابع مشابه
Normal immune system development in mice lacking the Deltex-1 RING finger domain.
The Notch signaling pathway controls several cell fate decisions during lymphocyte development, from T-cell lineage commitment to the peripheral differentiation of B and T lymphocytes. Deltex-1 is a RING finger ubiquitin ligase which is conserved from Drosophila to humans and has been proposed to be a regulator of Notch signaling. Its pattern of lymphoid expression as well as gain-of-function e...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2005
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.25.4.1437-1445.2005